Testing the God Hypothesis
In a sense, every science experiment is a test of the God hypothesis. This is because of the assumption of methodological naturalism, that is, the null hypothesis that God does not affect the outcome of experiments. If scientists ever obtained consistent data that could not be explained by any known natural processes, this would lend support to the hypothesis that God exists, and scientists would eagerly pursue this line of research. But the assumption of methodological naturalism holds; that is, we find no evidence of God's intervention in the natural world. Hence, we conclude that a god of the Judeo-Christian-Islamic type does not exist. While it is true, as the apologist will argue, that absence of evidence is not evidence of absence, it is nevertheless reasonable grounds for an assumption of non-existence, at least until reasonable evidence to the contrary is provided.
From a review of God: The Failed Hypothesis, by Victor Stenger.